As chief advisor to the Ministry of Health, Dr. Muzaffar drafted Pakistan’s transformative drug policy mandating: 90% local drug production, price controls on 622 essential medicines, and banning 1,200 irrational combinations. His “Affordable Medicines Framework” reduced antibiotic costs by 74% and enabled 120 local manufacturers to replace multinational dominance. Post-implementation surveys showed household medicine expenditure dropped 58% in low-income communities. The policy was later adopted as a WHO model for developing nations.